As a ligand,it can be used for the Buchwald,Suzuki etc., and the [4 +2] cycloaddition reaction.It can also be used for the synthesis of pentadiene,pentanediol,Acetyl propylene glycol,ketone and 2 - methyl tetrahydrofuran.In the pharmaceutical industry ,it is used for the synthesis of vitamin B1, chloroquine phosphate , primaquine phosphate and so on.